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| Research Status and Trends in Design Strategies and Mechanisms of Action for Antimicrobial Hydrogels |
| Received:August 11, 2025 Revised:August 27, 2025 |
| DOI：10.11980/j.issn.0254-508X.2026.01.004 |
| Key Words:hydrogel structural design antibacterial mechanism polymer inorganic material |
| Fund Project:山东省自然科学基金面上项目（ZR2023MC130）；全国重点实验室建设重大科研专项（2025ZDGZ02）。 |
| Author Name | Affiliation | Postcode | | SONG Xiaolan* | State Key Lab of Green Papermaking and Resource Recycling, Qilu University of Technology （Shandong Academy of Sciences）, Ji’nan, Shandong Province, 250353 | 250353 | | WU Chaojun* | State Key Lab of Green Papermaking and Resource Recycling, Qilu University of Technology （Shandong Academy of Sciences）, Ji’nan, Shandong Province, 250353 | 250353 | | CHEN Yehong | State Key Lab of Green Papermaking and Resource Recycling, Qilu University of Technology （Shandong Academy of Sciences）, Ji’nan, Shandong Province, 250353 | 250353 | | QIN Liming | State Key Lab of Green Papermaking and Resource Recycling, Qilu University of Technology （Shandong Academy of Sciences）, Ji’nan, Shandong Province, 250353 | 250353 |
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| Abstract:This paper systematically reviewed design strategies to enhance the antibacterial performance of hydrogels， analyzed the physical/chemical crosslinking mechanisms underlying their formation， and introduced antibacterial mechanisms of hydrogels incorporating natural polymers (such as chitosan， gelatin)， synthetic polymers (such as N-isopropylacrylamide， acrylamide), and inorganic materials (such as metals and their oxides， carbon materials). It proposed synergistic combinations of multiple antimicrobial mechanisms as a future trend for enhancing hydrogel antibacterial properties. |
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