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纳米纤维素作为药物载体的研究进展
Research Progress in the Application of Nanocellulose as Drug Delivery
收稿日期:2020-08-27  
DOI:10.11980/j.issn.0254-508X.2021.02.010
关键词:  纳米纤维素  药物载体  纤维素纳米晶体  纤维素纳米纤丝  细菌纤维素
Key Words:nanocellulose  drug delivery  cellulose nanocrystal  cellulose nanofibril  bacterial nanocellulose
基金项目:天津市教委科研计划资助项目(2018KJ098)。
作者单位邮编
陈甜甜 天津科技大学天津市制浆造纸重点实验室天津300457 300457
何星桦 天津科技大学天津市制浆造纸重点实验室天津300457 300457
蒋天艳 天津科技大学天津市制浆造纸重点实验室天津300457 300457
刘鹏涛 天津科技大学天津市制浆造纸重点实验室天津300457 300457
刘忠 天津科技大学天津市制浆造纸重点实验室天津300457 300457
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摘要:药物载体(Drug Delivery)通常由高分子纳米材料构成,可以控制药物释放速率,实现药物靶向运输功能。纳米纤维素具有良好的生物相容性、低毒性和可降解性等优良性能,可作为一种理想的新型药物载体材料。本文总结了近几年纤维素纳米晶体、纤维素纳米纤丝、细菌纤维素等作为药物载体的研究进展,并对其与药物分子的结合方式做了简单的介绍。
Abstract:Drug delivery is a kind of substance usually composed of polymer nanomaterials, which can change the release rate of drug and realize the drug targeted transport function. Nanocellulose has good biocompatibility, low toxicity and degradability, and can be used as an ideal new drug delivery material. In this paper, the research progress in the application of cellulose nanocrystal, cellulose nanofibril, and bacterial nanocellulose etc. as drug delivery was summarized, and the combination modes of nanocellulose and drug molecules were briefly introduced.
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